In the month of September in the year 1234, St. Clare sent four nuns from San Damiano to begin  a monastery dedicated to Saints Cosmas and Damian, commonly called San Cosimato.   This monastery eventually merged with another monastery to found San Lorenzo-in-Panisperna, from which came the nuns who brought the Poor Clare life to the United States.
The following is recounted of one of the nuns at San Cosimato:
Sister Violante Savelli, by birth a Roman princess, was of most exemplary conduct. She received the habit of the Order at San Cosimato. During her novitiate, she was grievously tempted to pusillanimity, thinking she would never be able to persevere in the observance of the Rule. This affliction caused her great sadness and despondency. Yet she bravely battled against the temptation, praying earnestly for strength and support. Being one night in prayer before the Blessed Sacrament, it seemed to her that a gleam of fire suddenly burst forth from the tabernacle, and rested upon her head. From that moment, all fear and timidity vanished, and, ever afterwards she excelled all the rest in the exact observance of the Religious life. Having reached the advanced age of one hundred years, she still attended midnight office, remaining standing the whole time, without ever leaning against anything for support.